CAGT publications

Corneo, B., Faga, G.,(…)Batlle-Morera, L. (2026). The transformative impact of stem cell core facilities in biomedical research. Stem Cell Reports, 103047. https://doi.org/10.1016/j.stemcr.2026.103047

Macedo, T., De Guidi, C.,(…)Alves-Lopes, J. P. (2026). Human iPSCs derived from cryopreserved testicular somatic cells enable germline regeneration in childhood cancer survivors. Human Reproduction Open, 2026(3). https://doi.org/10.1093/hropen/hoag054

Karlsson, O., Pandiloski, N.,(…)Jakobsson, J. (2026). Loss of SETDB1-mediated H3K9me3 in human neural progenitor cells leads to transcriptional activation of L1 retrotransposons. Nucleic Acids Research, 54(4). https://doi.org/10.1093/nar/gkag100

Gerdes, P., Karlsson, O.,(…)Jakobsson, J. (2025). Retroviral insertions contributed to the divergence of human and chimpanzee brains. bioRxiv. https://doi.org/10.64898/2025.12.12.693858

Adami, A., Garza, R.,(…)Jakobsson, J. (2025). LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. Cell Genom, 100979. https://doi.org/10.1016/j.xgen.2025.100979

Horvath, V., Garza, R.,(…)Jakobsson, J. (2024). Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease. Nat Struct Mol Biol, 31(10), 1543–1556. https://doi.org/10.1038/s41594-024-01320-8

Garza, R., Atacho, D. A. M.,(…)Jakobsson, J. (2023). LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification. Sci Adv, 9(44), eadh9543. https://doi.org/10.1126/sciadv.adh9543

Pircs, K., Drouin-Ouellet, J.,(…)Jakobsson, J. (2022). Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease. Brain, 145(9), 3035–3057. https://doi.org/10.1093/brain/awab473

Johansson, P. A., Brattås, P. L.,(…)Cataldo, R. (2022). A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development. Cell Stem Cell, 29(1), 52–69. e58.

Johansson, P. A., Adami, A.,(…)Jakobsson, J. (2022). CRISPRi-mediated transcriptional silencing in iPSCs for the study of human brain development. STAR Protoc, 3(2), 101285. https://doi.org/10.1016/j.xpro.2022.101285

Martinez Curiel, R., Tsupykov, O.,(…)Palma Tortosa, S. (2026). Efficient generation of human oligodendrocyte grafts that restore myelin in adult human brain tissue. bioRxiv, 2025.2002.2028.640804. https://doi.org/10.1101/2025.02.28.640804

Thakore, R., Alden, M.,(…)Klementieva, O. (2026). Early Amyloid Formation and Neuroinflammatory Response in a Bigenic Mouse Model Expressing Human alpha-Synuclein and Abeta. Parkinsons Dis, 2026, 7303965. https://doi.org/10.1155/padi/7303965

Ofori, J. K., Ruhrmann, S.,(…)Ling, C. (2026). Cell-specific DNA methylation in human alpha and beta cells regulates gene expression in type 2 diabetes. Nat Metab, 8(4), 957–980. https://doi.org/10.1038/s42255-026-01498-9

Magnusson, R., Hägg, A.,(…)Synnergren, J. (2026). AI-driven Quality Control of cell-based ATMPs: Automated, Accurate, and Affordable. Cytotherapy, 102135. https://doi.org/https://doi.org/10.1016/j.jcyt.2026.102135

Hagg, A., Wood, R.,(…)Falk, A. (2026). Toward standardized iPSC testing: Insights from a multi-year international Quality Assessment Round. Stem Cell Reports, 21(4), 102857. https://doi.org/10.1016/j.stemcr.2026.102857

Singh, T., Kalamajski, S.,(…)Fex, M. (2025). Modeling Genetic Risk of beta-Cell Dysfunction in Human Induced Pluripotent Stem Cells From Patients Carrying the MTNR1B Risk Variant. J Pineal Res, 77(5), e70073. https://doi.org/10.1111/jpi.70073

Prithiviraj, S., Garcia, A. G.,(…)Bourgine, P. E. (2025). Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines. eLife. https://doi.org/10.7554/elife.96941.2

Martinez-Curiel, R., Rincón-Cerrada, P.,(…)Palma-Tortosa, S. (2025). Rapid and efficient generation of human oligodendrocytes myelinating adult human cortical neurons. bioRxiv, 2025.2002.2028.640804. https://doi.org/10.1101/2025.02.28.640804

Henriques-Oliveira, L., Altman, A. R.,(…)Pereira, C. F. (2025). Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity. Immunity, 58(10), 2419–2438 e2413. https://doi.org/10.1016/j.immuni.2025.08.001

Dorazehi, F., Francesconi, C.,(…)Douse, C. H. (2025). MORC2 directs transcription-dependent CpG methylation of human LINE-1 transposons in early neurodevelopment. bioRxiv, 2025.2006.2011.658943. https://doi.org/10.1101/2025.06.11.658943

Calderon, A. S., Ghazanfari, R.,(…)Boiers, C. (2025). Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state. Leukemia, 39(9), 2099–2111. https://doi.org/10.1038/s41375-025-02665-9

Ascic, E., Fontanari, G.,(…)Pereira, C. F. (2025). Tractable In Vivo Reprogramming of Tumor Cells to Type 1 Conventional Dendritic Cell-like Cells. J Vis Exp(222). https://doi.org/10.3791/68739

Pandiloski, N., Horvath, V.,(…)Douse, C. H. (2024). DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor. Nat Commun, 15(1), 7534. https://doi.org/10.1038/s41467-024-50765-4

Ascic, E., Akerstrom, F.,(…)Pereira, C. F. (2024). In vivo dendritic cell reprogramming for cancer immunotherapy. Science, 386(6719), eadn9083. https://doi.org/10.1126/science.adn9083

Canals, I., Comella-Bolla, A.,(…)Ahlenius, H. (2023). Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia. Brain Commun, 5(3), fcad158. https://doi.org/10.1093/braincomms/fcad158

Pimkova, K., Jassinskaja, M.,(…)Hansson, J. (2022). Quantitative analysis of redox proteome reveals oxidation-sensitive protein thiols acting in fundamental processes of developmental hematopoiesis. Redox Biol, 53, 102343. https://doi.org/10.1016/j.redox.2022.102343

Oburoglu, L., Mansell, E.,(…)Woods, N. B. (2022). Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence. EMBO Rep, 23(2), e54384. https://doi.org/10.15252/embr.202154384

Oburoglu, L., Mansell, E.,(…)Woods, N. B. (2021). Glutamine metabolism regulates endothelial to hematopoietic transition and hematopoietic lineage specification. Sci Rep, 11(1), 17589. https://doi.org/10.1038/s41598-021-97194-7

Ciesla, M., Ngoc, P. C. T.,(…)Bellodi, C. (2021). Oncogenic translation directs spliceosome dynamics revealing an integral role for SF3A3 in breast cancer. Mol Cell, 81(7), 1453–1468 e1412. https://doi.org/10.1016/j.molcel.2021.01.034

Canals, I., Ginisty, A.,(…)Ahlenius, H. (2018). Rapid and efficient induction of functional astrocytes from human pluripotent stem cells. Nat Methods, 15(9), 693–696. https://doi.org/10.1038/s41592-018-0103-2

Last updated: 25 Aug 2026

CAGT publications

Publications from collaborations (CAGT authors)

Publications from services (CAGT acknowledgement)