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Computational Genomics

Soneji group

Hematopoietic stem cells (HSCs) and their maintenance/differentiation are regulated by complex mechanisms including epigenetic changes and transcription factor regulatory networks. A snapshot of how these processes are working can be captured using next generation sequencing (NGS).

These techniques are presently being implemented at the level of the single cell, allowing us to measure the degree of heterogeneity present within a population of cells. This raises a number of computational challenges such as how to find sub-populations of cells (that may be functionally different) in amongst noisey data, and this is the focus of our lab.

Impact

List of Team Soneji's publications


Team

(name linked to profile in Lund University research portal)

Shamit Soneji

Principal Investigator, Shamit [dot] Soneji [at] med [dot] lu [dot] se

Stefan Lang

Postdoc, Stefan [dot] Lang [at] med [dot] lu [dot] se

Oscar Legetth

Software Engineer, Oscar [dot] Legetth [at] med [dot] lu [dot] se

Johan Rodhe

Software Engineer, Johan [dot] Rodhe [at] med [dot] lu [dot] se

Shamit Soneji

 

Shamit Soneji

Principal Investigator
PhD, Assistant Professor
Division of Molecular Hematology
Phone: +46 46 222 08 72
Email: shamit [dot] soneji [at] med [dot] lu [dot] se

Profile in Lund University research portal