Stem Cell Stars Seminar: Michele de Luca

Talk Title: "Epithelial stem cells and combined cell and gene therapy"

When: 02 April 2025 | 15:00 - 16:00 + mingle

Where: Segerfalksalen, BMC A10

Host: Principal Investigator Malin Parmar

Following the lecture, take the opportunity to mingle and connect with colleagues and fellow researchers over refreshments at our post-seminar gathering. This is a wonderful opportunity to expand your professional network and share ideas in a relaxed setting. 

All are welcome, and no registration is required!

About the Speaker:

Michele de Luca

• Professor of Biochemistry, University of Modena and Reggio Emilia
• Director, Centre for Regenerative Medicine “Stefano Ferrari,” University of Modena and Reggio Emilia
• Director, Interdepartmental Centre for Stem Cells and Regenerative Medicine, University of Modena and Reggio Emilia

Michele De Luca is a leading figure in translational medicine, well known for his pioneering work in human squamous epithelial stem cell biology and its application in cell and gene therapy. His early achievements include using epidermal stem cell cultures for treating severe burns and skin conditions such as vitiligo and piebaldism, as well as developing urethral and corneal stem cell cultures for regenerative therapies. Notably, De Luca and collaborator Graziella Pellegrini created Holoclar, the first EMA-approved stem cell-based therapy, which restores vision in patients with limbal stem cell deficiency. His studies on p63 and c/EBPδ have illuminated mechanisms of epithelial stem cell renewal and proliferative potential, while his advancements in ex vivo gene therapy have led to life-saving treatments for genetic disorders like junctional epidermolysis bullosa (JEB). De Luca's work has directly benefiting hundreds of patients with conditions such as burns, ocular injuries, and genetic skin diseases, and helpd to shape global guidelines for responsible stem cell research.

• Learn more about Michele de Luca's scientific activities